I don't think you'd replace a materialized view with pg_later, but it might help you populate or update your materialized view if you are trying to do that asynchronously. pglater.exec() works with DDL too!

I use it a lot for long running queries when doing data science and machine learning work, and a lot of times when executing queries from a jupyter notebook or CLI. That way if my jupyter kernel dies, my query execution continues even if the network or my environment has an issue. I've started using it a bit more with https://github.com/postgresml/postgresml for model training tasks too, since those can be quite long running depending on the situation.