Can someone knowledgeable compare PyPy, Numba and Cython? I mostly use Cython. Tried Numba also, it has very nice workflow when it works with autojit (when it doesn't error messages are pretty cryptic). With PyPy I don't understand why for example all that type information obtained from jit wouldn't be used to make something like Numba specialized functions or Cython modules (noob question but please answer).
Have you tried the cffi? I used to use cython, but since I found the cffi, I haven't looked back.
There are a lot of cffi c bindings. I used with success: