What’s the best resource to get started with Rust and make a desktop app?

There's always Electron, Wasm, and the few smatterings of decent GUI frameworks being worked on. Also https://github.com/tauri-apps/tauri which claims to be a... Light, more native Electron?

Just depends what you want. A common pattern is essentially to build your app as a Rust library or CLI binary that your GUI wraps in whatever is most convenient for the GUI