I found his remarks about how (modern, ML-based) AI is the winter for Lisp interesting and congruent with how I see things currently. At the end of the day, many of the hardest problems in computing are solved best by simply throwing more compute (esp. matrix and array), memory, and data at them. Today's Lisp machines are GPGPU.

I wonder, why single Lisp out for a winter? If solving computational problems moves away from writing programs and toward writing GPT prompts, then wouldn't that forecast a winter for every programming language?

When AI was about building grammars, trees, developing expert systems builds rules etc. symbol manipulation was king. Look at PAIP for some examples: https://github.com/norvig/paip-lisp

This paradigm has changed.