I somewhat wished that when Chrome switches to manifest v3, uBlock Origin would stop supporting Chrome and its clones.

Firefox is the only browser where uBlock Origin is actually working as intended, Chrome on the other hand (even in manifest v2) is blocking so many features that uBO isn't actually able to work as a privacy and anti-malware tool. CNAME uncloaking is essential because websites can counter any filter rule by just aliasing the Google Analytics domain but Chrome doesn't have an API for that. Instead you need a gigantic list of filter rules, one for each domain, making loading web pages slower.

uBO is even slower in Chrome because Chrome doesn't allow extensions to use wasm.

https://github.com/gorhill/uBlock/wiki/uBlock-Origin-works-b...