"Reagent is the recommended approach for building ClojureScript applications with Luminus."

Reagent is nice, but if you want global state management, re-frame adds most familiar concepts from redux but without as much boilerplate: https://github.com/day8/re-frame

I found Rum (https://github.com/tonsky/rum) to be a much more flexible choice. It doesn't force you into a single way of doing things, but rather offers a composable way of adding behavior to components using mixins. Especially for larger and more complex applications this proves to be a good tool.

Another thing which I really like about Rum is "isomorphic rendering" (not a good name, but I didn't invent it) — pre-rendering the DOM on the server instead of shipping an empty page to the client and requiring the client to render everything using JavaScript.