This looks really nice. It's a shame the name is so similar to an existing app though (Pyxel Edit, https://pyxeledit.com/)

My favourite 2D framework right now is is LOVE (love2d.org) - I'm using that to build stuff with/for my kids and it's just a joy to use. I'll probably write up some parent/child friendly tutorials at some point. I also like Monkey-2 (http://monkeycoder.co.nz/), but I only really use that when I want to do basic 3D stuff, because Love does the 2D stuff so well...