I have been a heavy Python user now about 15 years, but for me now I'm increasingly reaching for modern JavaScript and particularly TypeScript to do the things I would have traditionally done with Python.

ES modules, fat arrow expressions, and all the other nice new syntax and library features have made the language so more pleasant to use. In many ways the ergonomics of TypeScript in particular are far superior to Python now, and I find that really surprising.

I haven't yet found a replacement for Django (particularly the ORM/Admin/Forms combination) it is just so incredibly productive to use. So, I don't think I will be moving off it, but it's certainly not the growth language for me anymore.

I am going this way too. I recently tried to onboard a few contractors with limited python experience. It took several deep sessions to work out why they couldn't get an environment set up. After 10+ years I've never come across the install certificates command. There's still no way to get a dev environment with a specific version of Python working with one command that works reliably everywhere. pyenv isn't even packaged for Linux, you have to install from source.

This, plus Typescript's superior type system makes it very tempting for application development.

However I'll probably wait until there's a really good Jupyter Notebook equivalent...

https://github.com/n-riesco/ijavascript

I used this for interactive debugging AWS API calls using the AWS Javascript SDK. It worked great!