I too have just been running ARM Homebrew the past few days.
For the most part, no real complaints. It'll depend heavily on what you install, and obviously you have to be OK with compiling things, but yeah no real complaints so far here either.
Other than the Python scientific ecosystem, Rust is really the main thing in my end-user stack I'm waiting on since fzy, bat, exa, etc. still don't compile, but other than that I'm fairly OK.
Does Anaconda not work on ARM? Anyone tried this yet: