You will be accepting a decline in quality of life to move to SF for work (increase in salary is not congruent with your increased expenses), and must decide if its worth it.

I'd suggest looking for full stack remote jobs where you'll make $100k-130k/year while remaining in Ohio (if thats where you want to live). Leaving a support system/family behind if you have a child (and considering another child) is not trivial.

Work remote, live better, visit SF once or twice a year for conferences to network and mingle.

I've been leaning toward that perspective recently.

I actually had a remote job in the pipeline but they ended up not being able to pay a commensurate salary or benefits (i.e. it was a significant pay cut from what I'm making now).

At least this process has got me back to studying data structures and algorithms again, so perhaps I can interview at Google Pittsburgh again and try for a better outcome this time. Any tips for finding a good remote position?

Always be looking, and don't relax your criteria (compensation, work/life balance) because its remote.

Just because a position is advertised as on site doesn't mean you can't negotiate it to be remote.

Here are some remote job resources I keep bookmarked:

https://remotebase.io/

https://github.com/lukasz-madon/awesome-remote-job

https://remoteok.io/

https://weworkremotely.com/

https://stackoverflow.com/jobs/remote-developer-jobs

https://www.wfh.io/

https://jobmote.com/

Salary negotiation cheat sheet: http://salarytutor.com/wp-content/uploads/2015/08/Salary-Tut...