I'm curious to see if this means I'll be able to use Wine again on MacOS post-Catalina (10.15) when Apple removed 32-bit support. I'm still on an Intel-based machine back from 2019 so I'm hoping this means support in the near future when a new version is available on Homebrew.
Then again I might be interpreting the release notes incorrectly and getting my hopes up for nothing.
The Crossover version works well on post-Catalina systems. You can just buy it or... compile their code :) There is a gcenx build available here: https://github.com/Gcenx/homebrew-wine .