Indeed! If your dependencies are able to be command line programs that are shell scripted together, then you can in fact have an access policy on a per-dependency basis, using the pledge.com program linked on my website. So shell scripters rejoice.

But it gets better. If you build Python in the Cosmopolitan Libc repository:

    git clone https://github.com/jart/cosmopolitan
    cd cosmopolitan
    build/bootstrap/make.com -j8 o//third_party/python/python.com

Then you can use cosmo.pledge() directly from Python.

    $ o//third_party/python/python.com
    Python 3.6.14+ (Actually Portable Python) [GCC 9.2.0] on cosmo
    Type "help", "copyright", "credits" or "license" for more information.
    >>: import cosmo, socket
    >>: cosmo.pledge('stdio rpath wpath tty', None)
    >>: print('hi')
    hi
    >>: socket.socket()
    Traceback (most recent call last):
      File "", line 1, in 
      File "/zip/.python/socket.py", line 144, in __init__
        _socket.socket.__init__(self, family, type, proto, fileno)
    PermissionError: [Errno 1] EPERM/1/Operation not permitted

Since we didn't put "inet" in the pledge, you can now be certain your PyPi deps aren't spying on you or uploading your bitcoin wallet to the cloud. You can even use os.fork() to rapidly put each dependency in its own process, then call cosmo.pledge() afterwards to grant each component of your app its own maximally restrictive policy.

Cosmopolitan Python also ports OpenBSD's unveil() system call to Linux too. For example, to disallow all file system access, just call cosmo.unveil(None, None). You need a very recent version of Linux though. For instance, I use unveil() in production on GCE but I had to apt install linux-image-5.18.0-0.deb11.4-cloud-amd64 in order for Landlock LSM to be available to use unveil().