This is probably gonna be sacrilege to the Pythonians, but I often wish there was support for some SQL-like syntax when working with (pandas) data frames. It certainly would make the process a lot smoother for some tasks.
I'd love if someone took the next step from Pandas being influenced by R to port dplyr-esque syntax to it.
I've been working on a library over the past year that does exactly that, including generating dbplyr style SQL queries!
Would love your feedback :)