One thing to watch out for when doing something like this is that the Raspberry Pi will by default put your file system on the SD card it boots from. SD cards aren't meant to support a lot of write/erase cycles, so it's easy to end up with a corrupt SD card after a few months to a year depending on what you're doing on your Pi.
A workaround that can save you some headaches here is to only boot from the SD card (which means you're effectively only ever reading from the card), and then mount a filesystem on an external SSD drive. There are a couple of good guides here [1] [2].
[1]: https://www.stewright.me/2019/10/run-raspbian-from-a-usb-or-...
[2]: https://www.pragmaticlinux.com/2020/08/move-the-raspberry-pi...
Most writes are the logs, I use log2ram [1], it reduces SD writes substantially.