How would this go as a Django replacement? I still use Django for new projects, but find that I end up just putting a GraphQL API on top of the Django ORM. At face value, Ent seems to tick both those boxes, but with the efficiency of a compiled language.
Ent is not a full-featured web framework so you need to implement many of features by your own or use other libraries (e.g. http server and session management).
If you are only looking for ORM + GraphQL then I highly recommend trying Entgql, an Ent extension for GraphQL with Gqlgen library [1]. Once you define an ORM schema, it will generate GraphQL Query for Relay server. Still you need to implement GraphQL Mutations by your own but at least it will create Input types for you (both for Create/Update).