Is anyone there using Guix as a daily driver? Is it stable? Would love to hear some user experiences.

Usually with esoteric distros you run into problems with binary packages and packages based on uncommonly used languages.

It'll probably work as a daily driver if you mainly live in a web browser and don't do GPGPU/games/new languages/etc. If you don't mind building from source you can even do most of those.

For what it's worth the project seems very well structured and the contributors very competent and motivated. I am tracking the project.

> if you mainly live in a web browser and don't do GPGPU

For what it's worth, I use Guix and I've been able to do everything but CUDA just fine. (CUDA will never be supported in Guix as it requires proprietary drivers to function.) There are opencl packages, for example. It works well enough to run an Ethereum miner, Blender, and even games in WINE. I've been meaning to package AMD ROCm for better GPU compute support.

One of the issues I've run into with Nix was lack of OpenGL. Does Guix have similar issues?

Nix has OpenGL it just doesn't know how to find the driver on non NixOS distros by default, can fix it with this: https://github.com/guibou/nixGL