There's a product here that's been waiting to happen for awhile. I've been anticipating somebody cross-compiling another browser engine to WASM but this works, too.

Deliver your site only to the "inner browser" (that the user has no control over because it's heavily obfuscated and tricked-out with anti-debugging code) and you eliminate all ad blockers. Throw some DNS-over-HTTPS w/ certificate pinning in for good measure and you kill DNS-based ad blockers too.

Accessibility will be a challenge but if it sells that'll get "fixed".

(I think this idea is evil, BTW, but somebody is going to do it.)

Edit: As an aside this needs to go here, too. https://www.destroyallsoftware.com/talks/the-birth-and-death...